Searchable abstracts of presentations at key conferences in endocrinology

ea0056gp69 | Cardiovascular | ECE2018

Can monogenic severe hypertriglyceridemia be differentiated from polygenic forms through clinical features: data from APPROACH and COMPASS studies in FCS and non-FCS hypertriglyceridemic patients?

O'Dea Louis , MacDougall James , Digenio Andres , Hubbard Brant , Arca Marcello , Moriarty Patrick , Kastelein John , Bruckert Eric , Witztum Joseph

Introduction: Differentiation between familial chylomicronemia syndrome (FCS), a rare hypertriglyceridemia, and severe hypertriglyceridemia (sHTG; non-FCS) is challenging due to overlap in triglyceride (TG) levels and symptomology but important in disease management. Clinical characteristics that allow for reliable differentiation may exist in the presenting clinical features and primary diagnostic testing. The objective of this analysis was to assess whether readily obtainabl...